The HLA-G 14-base pair deletion allele and the deletion/deletion genotype are associated with persistent HBe antigenemia in chronic hepatis B infection.

doi:10.1016/j.humimm.2016.12.011

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Article

The HLA-G 14-base pair deletion allele and the deletion/deletion genotype are associated with persistent HBe antigenemia in chronic hepatis B infection.

Human immunology - 1 Feb 2017

Ferreira Sandro da Costa, Chachá Silvana Gama Florêncio, Souza Fernanda Fernandes, Teixeira Andreza Corrêa, Santana Rodrigo de Carvalho, Deghaide Neifi Hassan Saloun, Rodrigues Sandra, Marano Leonardo A, Mendes-Junior Celso Teixeira, Ramalho Leandra Naira Zambelli, Zucoloto Sérgio, Donadi Eduardo Antônio, Martinelli Ana de Lourdes Candolo

Abstract excerpt

BACKGROUND AND AIMS: HLA-G has well-recognized immunomodulatory properties, and this molecule is frequently expressed in the livers of hepatitis B virus (HBV)-infected patients. Because the HLA-G 14 bp-insertion/deletion polymorphism (rs371194629) has been associated with the magnitude of HLA-G expression, we evaluated this polymorphism in the recognized evolutionary forms of chronic HBV infection. METHODS: We...

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PMID: 28041834
DOI: 10.1016/j.humimm.2016.12.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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