Article
Autophagy-related IRGM genes confer susceptibility to ankylosing spondylitis in a Chinese female population: a case-control study.
Genes and immunity - 1 Jan 2017
Xia Q, Wang M, Yang X, Li X, Zhang X, Xu S, Shuai Z, Xu J, Fan D, Ding C, Pan F
Abstract excerpt
It is known that ankylosing spondylitis (AS) and inflammatory bowel disease (IBD) shared a common genetic component. The gist of current study is to assess the role of IBD-associated autophagy gene IRGM on AS susceptibility in a Chinese Han population. A total of 1270 unrelated subjects (643 AS and 627 controls) were enrolled. Two tag single-nucleotide polymorphisms (SNPs) (rs10065172 and rs4958846) were selected...
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