Molecular Profiling to Determine Clonality of Serial Magnetic Resonance Imaging/Ultrasound Fusion Biopsies from Men on Active Surveillance for Low-Risk Prostate Cancer.

doi:10.1158/1078-0432.CCR-16-1454

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Article

Molecular Profiling to Determine Clonality of Serial Magnetic Resonance Imaging/Ultrasound Fusion Biopsies from Men on Active Surveillance for Low-Risk Prostate Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Feb 2017

Palapattu Ganesh S, Salami Simpa S, Cani Andi K, Hovelson Daniel H, Lazo de la Vega Lorena, Vandenberg Kelly R, Bratley Jarred V, Liu Chia-Jen, Kunju Lakshmi P, Montgomery Jeffery S, Morgan Todd M, Natarajan Shyam, Huang Jiaoti, Tomlins Scott A, Marks Leonard S

Abstract excerpt

Purpose: To determine whether MRI/ultrasound (MRI/US) fusion biopsy facilitates longitudinal resampling of the same clonal focus of prostate cancer and to determine whether high-grade cancers can evolve from low-grade clones.Experimental Design: All men on active surveillance who underwent tracking MRI/US fusion biopsy of Gleason 6 prostate cancer, on at least two distinct occasions, between 2012 and 2014 were...

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Identifiers

PMID: 28031426
DOI: 10.1158/1078-0432.CCR-16-1454
PMCID: PMC5315613

Genes

ERG
IDH1
SPOP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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