Article
Beyond PSMA: The essential complementary role of MRI in staging prostate cancer with Low-PSMA expression phenotypes.
European journal of nuclear medicine and molecular imaging - 1 Feb 2026
Chen Ruohua, Wang Yining, Dong Liang, Zhao Haitao, Li Lianghua, Huang Gang, Liu Liu, Liu Jianjun
Abstract excerpt
PURPOSE: While prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) is a highly sensitive modality for staging prostate cancer, a notable subset of patients presents with negative findings, leading to potential under-diagnosis. The incremental diagnostic value of multiparametric magnetic resonance imaging (mpMRI) in this specific cohort remains poorly defined. This...
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