Article
Mycobacterium bovis Requires P27 (LprG) To Arrest Phagosome Maturation and Replicate within Bovine Macrophages.
Infection and immunity - 1 Mar 2017
Vázquez Cristina Lourdes, Bianco María Verónica, Blanco Federico Carlos, Forrellad Marina Andrea, Gutierrez Maximiliano Gabriel, Bigi Fabiana
Abstract excerpt
Mycobacterium bovis causes tuberculosis in a wide variety of mammals, with strong tropism for cattle and eventually humans. P27, also called LprG, is among the proteins involved in the mechanisms of the virulence and persistence of M. bovis and Mycobacterium tuberculosis Here, we describe a novel function of P27 in the interaction of M. bovis with its natural host cell, the bovine macrophage. We found that a...
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