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Article

Protective coding variants in CFH and PELI3 and a variant near CTRB1 are associated with age-related macular degeneration†.

Human molecular genetics - 1 Dec 2016

Yu Yi, Wagner Erin K, Souied Eric H, Seitsonen Sanna, Immonen Ilkka J, Häppölä Paavo, Raychaudhuri Soumya, Daly Mark J, Seddon Johanna M

Abstract excerpt

Although numerous common age-related macular degeneration (AMD) alleles have been discovered using genome-wide association studies, substantial disease heritability remains unexplained. We sought to identify additional common and rare variants associated with advanced AMD. A total of 4,332 cases and 25,268 controls of European ancestry from three different populations were genotyped using the Illumina Infinium...

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Source

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Identifiers

PMID: 28011711
DOI: 10.1093/hmg/ddw336
PMCID: PMC6078639

Genes

CFH
CTRB1
PELI3
APOH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Protective coding variants in CFH and PELI3 and a variant near CTRB1 are associated with age-related macular degeneration†.PMID 28011711Read ↗

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