Article

Protective coding variants in <i>CFH</i> and <i>PELI3</i> and a variant near <i>CTRB1</i> are associated with age-related macular degeneration

2015-12-11

Abstract excerpt

<h4>ABSTRACT</h4> Although >20 common frequency age-related macular degeneration (AMD) alleles have been discovered with genome-wide association studies, substantial disease heritability remains unexplained. In this study we sought to identify additional variants, both common and rare, that have an association with advanced AMD. We genotyped 4,332 cases and 25,268 controls of European ancestry from three differen...

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Literature Corpus work: 4dd25a6f-a0c6-51f6-a389-603d1e527815
DOI: 10.1101/034173

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