Article
Comparison of Tumor Recurrence After Resection of Highly- and Poorly-Metastatic Triple-negative Breast Cancer in Orthotopic Nude-Mouse Models.
Anticancer research - 1 Jan 2017
Yano Shuya, Takehara Kiyoto, Kishimoto Hiroyuki, Tazawa Hiroshi, Urata Yasuo, Kagawa Shunsuke, Fujiwara Toshiyoshi, Bouvet Michael, Hoffman Robert M
Abstract excerpt
BACKGROUND: Triple-negative breast cancer (TNBC), defined by the absence of receptors for estrogen, progesterone and human epithelial receptor 2, is a recalcitrant disease in need of effective therapy. We previously isolated highly-metastatic variants of the human TNBC cell line MDA-MB-231 using serial orthotopic implantation in nude mice. MATERIALS AND METHODS: In the present report, we compared local and...
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