Article
Role of galectin-3 in breast cancer metastasis: involvement of nitric oxide.
The American journal of pathology - 1 Mar 2002
Song Young K, Billiar Timothy R, Lee Yong J
Abstract excerpt
We investigated the role of galectin-3 in metastasis of human breast carcinoma BT549 cells using the experimental liver metastasis model. Underlying mechanisms were then elucidated using the liver/tumor co-culture and cell culture systems. After intrasplenic injection, galectin-3 cDNA transfected BT549 cells (BT549(gal-3 wt)) formed metastatic colonies in the liver, while galectin-3 null BT549 cells (BT549(par))...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
