Article
MIF Gene Polymorphism rs755622 Is Associated With Coronary Artery Disease and Severity of Coronary Lesions in a Chinese Kazakh Population: A Case-Control Study.
Medicine - 1 Jan 2016
Luo Jun-Yi, Xu Rui, Li Xiao-Mei, Zhou Yun, Zhao Qian, Liu Fen, Chen Bang-Dang, Ma Yi-Tong, Gao Xiao-Ming, Yang Yi-Ning
Abstract excerpt
Inflammation plays an important role in the pathogenesis of atherosclerosis. Recent studies indicate that macrophage migration inhibitory factor (MIF) is a potent proinflammatory cytokine which mediates the inflammatory process during atherosclerosis. The polymorphism of MIF gene (rs755622 [-173G/C], rs1007888, and rs2096525) were genotyped by TaqMan single nucleotide polymorphism (SNP) genotyping assay in 320...
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