Article
Association between -174G/C and -572G/C interleukin 6 gene polymorphisms and severe radiographic damage to the hands of Mexican patients with rheumatoid arthritis: a preliminary report.
Genetics and molecular research : GMR - 19 Dec 2016
Zavaleta-Muñiz S A, Gonzalez-Lopez L, Murillo-Vazquez J D, Saldaña-Cruz A M, Vazquez-Villegas M L, Martín-Márquez B T, Vasquez-Jimenez J C, Sandoval-Garcia F, Ruiz-Padilla A J, Fajardo-Robledo N S, Ponce-Guarneros J M, Rocha-Muñoz A D, Alcaraz-Lopez M F, Cardona-Müller D, Totsuka-Sutto S E, Rubio-Arellano E D, Gamez-Nava J I
Abstract excerpt
Several interleukin 6 gene (IL6) polymorphisms are implicated in susceptibility to rheumatoid arthritis (RA). It has not yet been established with certainty if these polymorphisms are associated with the severe radiographic damage observed in some RA patients, particularly those with the development of joint bone ankylosis (JBA). The objective of the present study was to evaluate the association between severe...
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