Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clock genes associate with white matter integrity in depressed bipolar patients.

Chronobiology international - 1 Jan 2017

Bollettini Irene, Melloni Elisa Maria Teresa, Aggio Veronica, Poletti Sara, Lorenzi Cristina, Pirovano Adele, Vai Benedetta, Dallaspezia Sara, Colombo Cristina, Benedetti Francesco

Abstract excerpt

Human genetic studies have implicated specific genes that constitute the molecular clock in the manifestation of bipolar disorder (BD). Among the clock genes involved in the control system of circadian rhythms, CLOCK 3111 T/C and Period3 (PER3) influence core psychopathological features of mood disorders, such as patterns of sleep, rest, and activity, diurnal preference, cognitive performances after sleep loss,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anisotropy
Share to Antidepressive Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CLOCK Proteins

Share to Myelin Sheath

Share to Period Circadian Proteins

Share to Sleep Wake Disorders

Share to White Matter

Source

Identifiers

PMID: 27996307
DOI: 10.1080/07420528.2016.1260026

Genes

CLOCK
PER3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clock genes associate with white matter integrity in depressed bipolar patients.PMID 27996307Read ↗

Association of increased genotypes risk for bipolar disorder with brain white matter integrity investigated with tract-based spatial statistics: Special Section on "Translational and Neuroscience Studies in Affective Disorders". Section Editor, Maria Nobile MD, PhD. This Section of JAD focuses on the relevance of translational and neuroscience studies in providing a better understanding of the neural basis of affective disorders. The main aim is to briefly summarise relevant research findings i…Semantic proximity Read ↗

White matter microstructure in bipolar disorder is influenced by the serotonin transporter gene polymorphism 5-HTTLPR.Semantic proximity Read ↗

Evidence of genetic overlap between circadian preference and brain white matter microstructureSemantic proximity Read ↗

Lithium and GSK3-β promoter gene variants influence white matter microstructure in bipolar disorder.Semantic proximity Read ↗

Chronotype and sleep quality as a subphenotype in association studies of clock genes in mood disorders.Semantic proximity Read ↗

Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega- and meta-analyses across 3033 individualsSemantic proximity Read ↗

Clock gene variants differentiate mood disorders.Semantic proximity Read ↗

Is the molecular clock ticking differently in bipolar disorder? Methylation analysis of the clock gene ARNTL.Semantic proximity Read ↗

Effects of ANK3 variation on gray and white matter in bipolar disorder.Semantic proximity Read ↗

Genetically mediated associations between chronotype and neuroimaging phenotypes in the UK Biobank: a Mendelian randomisation studySemantic proximity Read ↗

White matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imagingSemantic proximity Read ↗

Abnormal temporal lobe white matter as a biomarker for genetic risk of bipolar disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.