Is the molecular clock ticking differently in bipolar disorder? Methylation analysis of the clock gene ARNTL.

doi:10.1080/15622975.2016.1231421

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Article

Is the molecular clock ticking differently in bipolar disorder? Methylation analysis of the clock gene ARNTL.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Jan 2018

Bengesser Susanne A, Reininghaus Eva Z, Lackner Nina, Birner Armin, Fellendorf Frederike T, Platzer Martina, Kainzbauer Nora, Tropper Bernhard, Hörmanseder Christa, Queissner Robert, Kapfhammer Hans-Peter, Wallner-Liebmann Sandra J, Fuchs Robert, Petek Erwin, Windpassinger Christian, Schnalzenberger Mario, Reininghaus Bernd, Evert Bernd, Waha Andreas

Abstract excerpt

OBJECTIVES: The clock gene ARNTL is associated with the transcription activation of monoamine oxidase A according to previous literature. Thus, we hypothesised that methylation of ARNTL may differ between bipolar disorder (BD) and controls. METHODS: The methylation status of one CpG island covering the first exon of ARNTL (PS2) and one site in the 5' region of ARNTL (cg05733463) were analysed in patients with BD...

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PMID: 27739341
DOI: 10.1080/15622975.2016.1231421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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