Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

White matter microstructure in bipolar disorder is influenced by the serotonin transporter gene polymorphism 5-HTTLPR.

Genes, brain, and behavior - 1 Mar 2015

Benedetti F, Bollettini I, Poletti S, Locatelli C, Lorenzi C, Pirovano A, Smeraldi E, Colombo C

Abstract excerpt

Bipolar disorder (BD) is associated with signs of widespread disruption of white matter (WM) integrity. A polymorphism in the promoter of the serotonin transporter (5-HTTLPR) influenced functional cortico-limbic connectivity in healthy subjects and course of illness in BD, with the short (s) allele being associated with lower functional connectivity, and with earlier onset of illness and poor response to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Diffusion Tensor Imaging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Serotonin Plasma Membrane Transport Proteins

Share to White Matter

Source

Identifiers

PMID: 25704032
DOI: 10.1111/gbb.12206

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

White matter microstructure in bipolar disorder is influenced by the serotonin transporter gene polymorphism 5-HTTLPR.PMID 25704032Read ↗

Association of increased genotypes risk for bipolar disorder with brain white matter integrity investigated with tract-based spatial statistics: Special Section on "Translational and Neuroscience Studies in Affective Disorders". Section Editor, Maria Nobile MD, PhD. This Section of JAD focuses on the relevance of translational and neuroscience studies in providing a better understanding of the neural basis of affective disorders. The main aim is to briefly summarise relevant research findings i…Semantic proximity Read ↗

Lithium and GSK3-β promoter gene variants influence white matter microstructure in bipolar disorder.Semantic proximity Read ↗

SREBF-2 polymorphism influences white matter microstructure in bipolar disorder.Semantic proximity Read ↗

Genetic neuroimaging of bipolar disorder: a systematic 2017-2020 update.Semantic proximity Read ↗

Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega- and meta-analyses across 3033 individualsSemantic proximity Read ↗

Clock genes associate with white matter integrity in depressed bipolar patients.Semantic proximity Read ↗

Common genetic variation influencing human white matter microstructureSemantic proximity Read ↗

Frontal-limbic white matter pathway associations with the serotonin transporter gene promoter region (5-HTTLPR) polymorphism.Semantic proximity Read ↗

White Matter Tract Integrity Is Reduced in Depression and in Individuals With Genetic Liability to Depression.Semantic proximity Read ↗

Widespread white matter tract aberrations in youth with familial risk for bipolar disorder.Semantic proximity Read ↗

Gray matter abnormalities and associated familial risk endophenotype in individuals with first-episode bipolar disorder: Evidence from whole-brain voxel-wise meta-analysis.Semantic proximity Read ↗

Along-Tract Statistical Mapping of Microstructural Abnormalities in Bipolar Disorder: A Pilot StudySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.