Article
Interleukin (IL)-10 gene polymorphisms are associated with type 2 diabetes with and without nephropathy: a study of patients from the southeast region of Iran.
Inflammation - 1 Jun 2012
Arababadi Mohammad Kazemi, Reza Mirzaei Mohammad, Ali Sajadi Seyed Mohammad, Hassanshahi Gholamhossein, Ahmadabadi Behzad Nasiri, Salehabadi Vajihe Akbarpour, Derakhshan Reza, Kennedy Derek
Abstract excerpt
The impact of several environmental and genetic factors on diabetes and its complications is well documented. It has also been established that cytokines play a key role in the regulation of immune responses which have been shown to be important in the pathogenesis of diabetes. Studies showed that single-nucleotide polymorphisms within the -592 region of interleukin-10 (IL-10) are associated with the regulation...
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