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Article

Genes involved in angiogenesis and mTOR pathways are frequently mutated in Asian patients with pancreatic neuroendocrine tumors.

International journal of biological sciences - 1 Jan 2016

Chou Wen-Chi, Lin Po-Han, Yeh Yi-Chen, Shyr Yi-Ming, Fang Wen-Liang, Wang Shin-E, Liu Chun-Yu, Chang Peter Mu-Hsin, Chen Ming-Han, Hung Yi-Ping, Li Chung-Pin, Chao Yee, Chen Ming-Huang

Abstract excerpt

Introduction: To address the issue of limited data on and inconsistent findings for genetic alterations in pancreatic neuroendocrine tumors (pNETs), we analyzed sequences of known pNET-associated genes for their impact on clinical outcomes in a Taiwanese cohort. Methods: Tissue samples from 40 patients with sporadic pNETs were sequenced using a customized sequencing panel that analyzed 43 genes with either an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multiple Endocrine Neoplasia Type 1

Share to Neovascularization, Pathologic

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Source

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Identifiers

PMID: 27994516
DOI: 10.7150/ijbs.16233
PMCID: PMC5166493

Genes

ATRX
MEN1
DAXX
VHL
AKT1
ANGPT1
ANGPT2
ASCL1
ATM
PSIP1
PTEN
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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