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Article

CUL4A functions as an oncogene in ovarian cancer and is directly regulated by miR-494.

Biochemical and biophysical research communications - 25 Nov 2016

Han Xiaoni, Fang Ziling, Wang Heng, Jiao Rongfang, Zhou Jing, Fang Nian

Abstract excerpt

Cullin 4A (CUL4A), as a well-defined oncogene, has been reported to be upregulated in ovarian cancer clinically. However, the biological functions of CUL4A and the molecular mechanism underlying its upregulation in ovarian cancer remains unknown throughly. Here, we show that expression of CUL4A is significantly higher in ovarian cancer tissues compared to corresponding non-cancerous tissues. Moreover, silencing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27983981
DOI: 10.1016/j.bbrc.2016.10.114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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