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Cell division cycle associated 5 promotes colorectal cancer progression by activating the ERK signaling pathway

26 Feb 2019

Abstract excerpt

Cell division cycle associated 5 (CDCA5) is implicated in the development and progression of a variety of human cancers. Functional significance of CDCA5 in colorectal cancer (CRC), however, has not been investigated. Using a combination of on-line data mining, biochemistry, and molecular biology, we examined the potential oncogenic activity of CDCA5 and the underlying mechanisms. Experiments with human tissue...

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PMID: 30808873
DOI: 10.1038/s41389-019-0123-5

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