Article
Impact of SNPs on methylation readouts by Illumina Infinium HumanMethylation450 BeadChip Array: implications for comparative population studies.
BMC genomics - 25 Nov 2015
Daca-Roszak Patrycja, Pfeifer Aleksandra, Żebracka-Gala Jadwiga, Rusinek Dagmara, Szybińska Aleksandra, Jarząb Barbara, Witt Michał, Ziętkiewicz Ewa
Abstract excerpt
BACKGROUND: Infinium HumanMethylation 450 BeadChip Arrays by Illumina (Illumina HM450K) are among the most popular CpG microarray platforms widely used in biological and medical research. Several recent studies highlighted the potentially confounding impact of the genomic variation on the results of methylation studies performed using Illumina's Infinium methylation probes. However, the complexity of SNPs impact...
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