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Exercise Prevents Cognitive Function Decline and Demyelination in the White Matter of APP/PS1 Transgenic AD Mice

30 Dec 2016

Abstract excerpt

BACKGROUND: Whether exercise could delay the cognitive function decline and structural changes in Alzheimer's disease (AD) are not fully understood. METHODS: 6-month-old male APP/PS1 double transgenic mice ran four months and then the effects of exercise on the cognitive function and the white matter of AD were investigated. RESULTS: The mean escape latency of the excercised group was significantly shortened when...

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PMID: 27978791
DOI: 10.2174/1567205014666161213121353

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