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Article

Association of Heme Oxygenase 1 with Lung Protection in Malaria-Associated ALI/ARDS.

Mediators of inflammation - 1 Jan 2016

Pereira Marcelo L M, Ortolan Luana S, Sercundes Michelle K, Debone Daniela, Murillo Oscar, Lima Flávia A, Marinho Claudio R F, Epiphanio Sabrina

Abstract excerpt

Malaria is a serious disease, caused by the parasite of the genus Plasmodium, which was responsible for 440,000 deaths in 2015. Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is one of the main clinical complications in severe malaria. The murine model DBA/2 reproduces the clinical signs of ALI/ARDS in humans, when infected with Plasmodium berghei ANKA. High levels of HO-1 were reported in cases...

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Identifiers

PMID: 27974865
DOI: 10.1155/2016/4158698
PMCID: PMC5126464

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