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Article

Parasite burden and CD36-mediated sequestration are determinants of acute lung injury in an experimental malaria model.

PLoS pathogens - 16 May 2008

Lovegrove Fiona E, Gharib Sina A, Peña-Castillo Lourdes, Patel Samir N, Ruzinski John T, Hughes Timothy R, Liles W Conrad, Kain Kevin C

Abstract excerpt

Although acute lung injury (ALI) is a common complication of severe malaria, little is known about the underlying molecular basis of lung dysfunction. Animal models have provided powerful insights into the pathogenesis of severe malaria syndromes such as cerebral malaria (CM); however, no model of malaria-induced lung injury has been definitively established. This study used bronchoalveolar lavage (BAL),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18483551
DOI: 10.1371/journal.ppat.1000068
PMCID: PMC2364663

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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