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Article

Enhanced Production of Itaconic Acid through Development of Transformed Fungal Strains of Aspergillus terreus.

Journal of microbiology and biotechnology - 28 Feb 2017

Shin Woo-Shik, Park Boonyoung, Lee Dohoon, Oh Min-Kyu, Chun Gie-Taek, Kim Sangyong

Abstract excerpt

Metabolic engineering with a high-yielding mutant, A. terreus AN37, was performed to enhance the production of itaconic acid (IA). Reportedly, the gene cluster for IA biosynthesis is composed of four genes: reg (regulator), mtt (mitochondrial transporter), cad (cis-aconitate decarboxylase), and mfs (membrane transporter). By overexpressing each gene of the IA gene cluster in A. terreus AN37 transformed by the...

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PMID: 27974733
DOI: 10.4014/jmb.1611.11054

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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