Article
Deletion analysis of the itaconic acid biosynthesis gene cluster components in Aspergillus pseudoterreus ATCC32359.
Applied microbiology and biotechnology - 1 May 2020
Deng Shuang, Dai Ziyu, Swita Marie, Pomraning Kyle R, Hofstad Beth, Panisko Ellen, Baker Scott, Magnuson Jon
Abstract excerpt
The filamentous fungus Aspergillus terreus has been successfully used for industrial production of itaconic acid (IA) for many years. The IA biosynthesis pathway has recently been characterized at a molecular genetic level as an IA gene cluster by a clone-based transcriptomic approach. The cluster consists of four genes, including genes for cis-aconitic acid decarboxylase (cadA), a predicted transcription factor...
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