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Strain improvement of industrially important microorganisms based on resistance to toxic metabolites and abiotic stress.

Journal of basic microbiology - 1 Jun 2017

Fiedurek Jan, Trytek Mariusz, Szczodrak Janusz

Abstract excerpt

Improvement of the biosynthetic capabilities of industrially relevant microbes to produce desired metabolites in higher quantities is one of the important topics of modern biotechnology. In this article, different strategies of improvement of mutated microbial strains are briefly described. This is followed by the first comprehensive review of the literature on obtaining high yielding microorganisms, that is,...

Topics

Antimetabolites
Bacteria
Biotechnology
Drug Tolerance
Fermentation
Industrial Microbiology
Metabolic Networks and Pathways
Mutation
Solvents
Stress, Physiological

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PMID: 28370185
DOI: 10.1002/jobm.201600710

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