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Article

MicroRNA expressing profiles in A53T mutant alpha-synuclein transgenic mice and Parkinsonian.

Oncotarget - 3 Jan 2017

Mo Mingshu, Xiao Yousheng, Huang Shuxuan, Cen Luan, Chen Xiang, Zhang Limin, Luo Qin, Li Shaomin, Yang Xinling, Lin Xian, Xu Pingyi

Abstract excerpt

α-synuclein gene mutations can cause α-synuclein protein aggregation in the midbrain of Parkinson's disease (PD) patients. MicroRNAs (miRNAs) play a key role in the metabolism of α-synuclein but the mechanism involved in synucleinopathy remains unclear. In this study, we investigated the miRNA profiles in A53T-α-synuclein transgenic mice and analyzed the candidate miRNAs in the cerebrospinal fluid (CSF) of PD...

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Source

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Identifiers

PMID: 27965467
DOI: 10.18632/oncotarget.13905
PMCID: PMC5352072

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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