Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium tuberculosis Infections

29 Nov 2016

Abstract excerpt

The circulating antibody repertoire encodes a patient’s health status and pathogen exposure history, but identifying antibodies with diagnostic potential usually requires knowledge of the antigen(s). We previously circumvented this problem by screening libraries of bead-displayed small molecules against case and control serum samples to discover “epitope surrogates” (ligands of IgGs enriched in the case sample)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemical Synthesis and Analysis
Share to Monoclonal and Polyclonal Antibodies Research
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27957856
DOI: 10.1021/acschembio.6b00855

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium tuberculosis InfectionsPMID 27957856Read ↗

Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restrictionSemantic proximity Read ↗

Microarray-based selection of a serum biomarker panel that can discriminate between latent and active pulmonary TBSemantic proximity Read ↗

Antibody-Fab and -Fc features promote <i>Mycobacterium tuberculosis</i> restrictionSemantic proximity Read ↗

Pattern Recognition in Pulmonary Tuberculosis Defined by High Content Peptide Microarray Chip Analysis Representing 61 Proteins from M. tuberculosisSemantic proximity Read ↗

Profiling Antibodies to Mycobacterium tuberculosis by Multiplex Microbead Suspension Arrays for Serodiagnosis of TuberculosisSemantic proximity Read ↗

Fc-engineered antibodies leverage neutrophils to drive control of <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

Peptide-driven identification of TCRs reveals dynamics and phenotypes of CD4 T cells in tuberculosis.Semantic proximity Read ↗

Identification of disease-specific motifs in the antibody specificity repertoire via next-generation sequencingSemantic proximity Read ↗

A hybridization target enrichment approach for pathogen genomicsSemantic proximity Read ↗

High-throughput single-cell analysis reveals fully human Omp38-specific monoclonal antibodies against Acinetobacter baumanniiSemantic proximity Read ↗

In-depth immunophenotyping with mass cytometry during TB treatment reveals non-canonical T-cell subsets associated with sputum culture conversionSemantic proximity Read ↗

Dynamic antibody responses to the <i>Mycobacterium tuberculosis</i> proteomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.