Article
A genome-wide analysis in cluster headache points to neprilysin and PACAP receptor gene variants.
The journal of headache and pain - 1 Dec 2016
Bacchelli Elena, Cainazzo Maria Michela, Cameli Cinzia, Guerzoni Simona, Martinelli Angela, Zoli Michele, Maestrini Elena, Pini Luigi Alberto
Abstract excerpt
BACKGROUND: Cluster Headache (CH) is a severe primary headache, with a poorly understood pathophysiology. Complex genetic factors are likely to play a role in CH etiology; however, no confirmed gene associations have been identified. The aim of this study is to identify genetic variants influencing risk to CH and to explore the potential pathogenic mechanisms. METHODS: We have performed a genome-wide association...
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