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Article

Decreased white matter FA values in the left inferior frontal gyrus is a possible intermediate phenotype of schizophrenia: evidences from a novel group strategy.

European archives of psychiatry and clinical neuroscience - 1 Feb 2018

Ou Jianjun, Lyu Hailong, Hu Maorong, Li Jun, Guo Wenbin, Guo Xiaofeng, Li Lihua, Zheng Junjie, Wei Qinling, Liu Feng, He Zhong, Wang Juan, Liu Fang, Wu Renrong, Chen Jindong, Li Lehua, Hu Bin, Chen Huafu, Zhao Jingping

Abstract excerpt

Intermediate phenotype could be used to investigate genetic susceptibility. However, genetic and environmental heterogeneity may interfere with identification of intermediate phenotypes. In this study, we minimized these interferences by using a novel group strategy. A total of 22 drug-naive and first-episode schizophrenia (FES) patients, along with 22 of their kin healthy siblings (HS), 22 non-kin healthy...

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PMID: 27942861
DOI: 10.1007/s00406-016-0752-z

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FES

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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