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Article

Mean diffusivity and fractional anisotropy as indicators of disease and genetic liability to schizophrenia.

Journal of psychiatric research - 1 Jul 2011

Clark Kristi A, Nuechterlein Keith H, Asarnow Robert F, Hamilton Liberty S, Phillips Owen R, Hageman Nathan S, Woods Roger P, Alger Jeffry R, Toga Arthur W, Narr Katherine L

Abstract excerpt

The goals of this study were to first determine whether the fractional anisotropy (FA) and mean diffusivity (MD) of major white matter pathways associate with schizophrenia, and secondly to characterize the extent to which differences in these metrics might reflect a genetic predisposition to schizophrenia. Differences in FA and MD were identified using a comprehensive atlas-based tract mapping approach using...

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Identifiers

PMID: 21306734
DOI: 10.1016/j.jpsychires.2011.01.006
PMCID: PMC3109158

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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