Article
Multi-omics approach to study global changes in a triclosan-resistant mutant strain of Acinetobacter baumannii ATCC 17978.
International journal of antimicrobial agents - 1 Jan 2017
Fernando Dinesh M, Chong Patrick, Singh Manu, Spicer Victor, Unger Mark, Loewen Peter C, Westmacott Garrett, Kumar Ayush
Abstract excerpt
Acinetobacter baumannii AB042, a triclosan-resistant mutant strain, was examined for modulated gene expression using whole-genome sequencing, transcriptomics and proteomics in order to understand the mechanism of triclosan resistance as well as its impact on A. baumannii. Data revealed modulated expression of the fatty acid metabolism pathway, co-factors known to play a role in the synthesis of fatty acids, as...
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