Article
Using Systems Genetics to Understanding the Etiology of Complex Disease.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Ram Ramesh, Morahan Grant
Abstract excerpt
Here, we discuss Systems Genetics applications for systematic evaluation of candidate causal genes together with follow-up bioinformatics pathway analysis. The aim of this chapter is to illustrate analytic procedures and we provide examples in the context of Type 1 diabetes (T1day), the risk of which is conferred by over 60 loci. We also describe the Type 1 Diabetes Systems Genetics website and provide a guide...
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