Article
Systems genetics approaches to understand complex traits.
Nature reviews. Genetics - 1 Jan 2014
Civelek Mete, Lusis Aldons J
Abstract excerpt
Systems genetics is an approach to understand the flow of biological information that underlies complex traits. It uses a range of experimental and statistical methods to quantitate and integrate intermediate phenotypes, such as transcript, protein or metabolite levels, in populations that vary for traits of interest. Systems genetics studies have provided the first global view of the molecular architecture of...
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