Article
The association of BTLA gene polymorphisms with non-small lung cancer risk in smokers and never-smokers.
Frontiers in immunology - 1 Jan 2022
Andrzejczak Anna, Partyka Anna, Wiśniewski Andrzej, Porębska Irena, Pawełczyk Konrad, Ptaszkowski Kuba, Kuśnierczyk Piotr, Jasek Monika, Karabon Lidia
Abstract excerpt
Introduction: Lung cancer is the predominant cause of death among cancer patients and non-small cell lung cancer (NSCLC) is the most common type. Cigarette smoking is the prevailing risk factor for NSCLC, nevertheless, this cancer is also diagnosed in never-smokers. B and T lymphocyte attenuator (BTLA) belongs to immunological checkpoints which are key regulatory molecules of the immune response. A growing body...
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