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Article

MiR-34a-5p and miR-452-5p: The Novel Regulators of Pancreatic Endocrine Dysfunction in Diabetic Zucker Rats?

1 Jan 2021

Abstract excerpt

Objective: The pancreatic endocrinal system dominates the regulation of blood glucose levels in vivo, and the dysfunction of pancreatic endocrine -cells is a major cause of the occurrence and development of Type 2 diabetes (T2D). Although microRNA (miRNA) have been found to be key regulators of pancreatic -cells proliferation, differentiation and apoptosis, the underlying mechanism remains enigmatic. The aim of...

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PMID: 34400887
DOI: 10.7150/ijms.62843

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