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Article

FGF23 Is Not Required to Regulate Fetal Phosphorus Metabolism but Exerts Effects Within 12 Hours After Birth.

Endocrinology - 1 Feb 2017

Ma Yue, Kirby Beth J, Fairbridge Nicholas A, Karaplis Andrew C, Lanske Beate, Kovacs Christopher S

Abstract excerpt

Loss of fibroblast growth factor-23 (FGF23) causes hyperphosphatemia, extraskeletal calcifications, and early mortality; excess FGF23 causes hypophosphatemia with rickets or osteomalacia. However, FGF23 may not be important during fetal development. FGF23 deficiency (Fgf23 null) and FGF23 excess (Phex null) did not alter fetal phosphorus or skeletal parameters. In this study, we further tested our hypothesis that...

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Source

Open in PubMed Open full text

Identifiers

PMID: 27929669
DOI: 10.1210/en.2016-1369
PMCID: PMC5413075

Genes

FGF23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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FGF23 Is Not Required to Regulate Fetal Phosphorus Metabolism but Exerts Effects Within 12 Hours After Birth.PMID 27929669Read ↗

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