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Article

Coordinated inhibition of C/EBP by Tribbles in multiple tissues is essential for Caenorhabditis elegans development.

BMC biology - 7 Dec 2016

Kim Kyung Won, Thakur Nishant, Piggott Christopher A, Omi Shizue, Polanowska Jolanta, Jin Yishi, Pujol Nathalie

Abstract excerpt

BACKGROUND: Tribbles proteins are conserved pseudokinases that function to control kinase signalling and transcription in diverse biological processes. Abnormal function in human Tribbles has been implicated in a number of diseases including leukaemia, metabolic syndromes and cardiovascular diseases. Caenorhabditis elegans Tribbles NIPI-3 was previously shown to activate host defense upon infection by promoting...

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Identifiers

PMID: 27927209
DOI: 10.1186/s12915-016-0320-z
PMCID: PMC5141650

Genes

EBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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