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Article

Allele-specific expression in the human heart and its application to postoperative atrial fibrillation and myocardial ischemia.

Genome medicine - 6 Dec 2016

Sigurdsson Martin I, Saddic Louis, Heydarpour Mahyar, Chang Tzuu-Wang, Shekar Prem, Aranki Sary, Couper Gregory S, Shernan Stanton K, Seidman Jon G, Body Simon C, Muehlschlegel Jochen D

Abstract excerpt

BACKGROUND: Allele-specific expression (ASE) is differential expression of each of the two chromosomal alleles of an autosomal gene. We assessed ASE patterns in the human left atrium (LA, n = 62) and paired samples from the left ventricle (LV, n = 76) before and after ischemia, and tested the utility of differential ASE to identify genes associated with postoperative atrial fibrillation (poAF) and myocardial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27923400
DOI: 10.1186/s13073-016-0381-1
PMCID: PMC5139013

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GSN
ZHX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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