Article
Post-operative atrial fibrillation examined using whole-genome RNA sequencing in human left atrial tissue.
BMC medical genomics - 2 May 2017
Sigurdsson Martin I, Saddic Louis, Heydarpour Mahyar, Chang Tzuu-Wang, Shekar Prem, Aranki Sary, Couper Gregory S, Shernan Stanton K, Muehlschlegel Jochen D, Body Simon C
Abstract excerpt
BACKGROUND: Both ambulatory atrial fibrillation (AF) and post-operative AF (poAF) are associated with substantial morbidity and mortality. Analyzing the tissue-specific gene expression in the left atrium (LA) can identify novel genes associated with AF and further the understanding of the mechanism by which previously identified genetic variants associated with AF mediate their effects. METHODS: LA free wall...
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