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Article

Extracts from two ubiquitous Mediterranean plants ameliorate cellular and animal models of neurodegenerative proteinopathies.

Neuroscience letters - 18 Jan 2017

Briffa Michelle, Ghio Stephanie, Neuner Johanna, Gauci Alison J, Cacciottolo Rebecca, Marchal Christelle, Caruana Mario, Cullin Christophe, Vassallo Neville, Cauchi Ruben J

Abstract excerpt

A signature feature of age-related neurodegenerative proteinopathies is the misfolding and aggregation of proteins, typically amyloid-β (Aβ) in Alzheimer's disease (AD) and α-synuclein (α-syn) in Parkinson's disease (PD), into soluble oligomeric structures that are highly neurotoxic. Cellular and animal models that faithfully replicate the hallmark features of these disorders are being increasing exploited to...

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PMID: 27919712
DOI: 10.1016/j.neulet.2016.11.058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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