Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

m6A modulates neuronal functions and sex determination in Drosophila.

Nature - 8 Dec 2016

Lence Tina, Akhtar Junaid, Bayer Marc, Schmid Katharina, Spindler Laura, Ho Cheuk Hei, Kreim Nastasja, Andrade-Navarro Miguel A, Poeck Burkhard, Helm Mark, Roignant Jean-Yves

Abstract excerpt

N6-methyladenosine RNA (m6A) is a prevalent messenger RNA modification in vertebrates. Although its functions in the regulation of post-transcriptional gene expression are beginning to be unveiled, the precise roles of m6A during development of complex organisms remain unclear. Here we carry out a comprehensive molecular and physiological characterization of the individual components of the methyltransferase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine
Share to Alternative Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Behavior, Animal

Share to Methyltransferases

Share to Nervous System

Share to Protein Subunits

Share to RNA-Binding Proteins

Share to Sex Determination Processes

Source

Identifiers

PMID: 27919077
DOI: 10.1038/nature20568

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

m6A modulates neuronal functions and sex determination in Drosophila.PMID 27919077Read ↗

Biological functions of m6A methyltransferasesSemantic proximity Read ↗

Main N6-Methyladenosine Readers: YTH Family Proteins in CancersSemantic proximity Read ↗

Role of Hakai in m6A modification pathway in Drosophila.Semantic proximity Read ↗

Context-dependent functional compensation between Ythdf m6A readersSemantic proximity Read ↗

The m6A pathway facilitates sex determination in Drosophila.Semantic proximity Read ↗

m 6 A RNA Modification Determines Cell Fate by Regulating mRNA DegradationSemantic proximity Read ↗

m6A demethylase OsALKBH5 is required for double-strand break formation and repair by affecting mRNA stability in rice meiosis.Semantic proximity Read ↗

N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3'-end processing.Semantic proximity Read ↗

Catalytic activity of the Bin3/MEPCE methyltransferase domain is dispensable for 7SK snRNP function in <i>Drosophila melanogaster</i>Semantic proximity Read ↗

tRNA 2’-O-methylation modulates small RNA silencing and life span in <i>Drosophila</i>Semantic proximity Read ↗

The regulatory role of m6A modification in the maintenance and differentiation of embryonic stem cellsSemantic proximity Read ↗

The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.