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Article

Predicting CYP2D6 phenotype from resting brain perfusion images by gradient boosting.

Psychiatry research. Neuroimaging - 30 Jan 2017

Napolitano Giulio, Stingl Julia C, Schmid Matthias, Viviani Roberto

Abstract excerpt

The cytochrome P450 enzyme 2D6 is involved in the metabolism of 20% of all commonly used drugs, including many psychotropic drugs and CNS-active substances. CYP2D6 is among the CYP enzymes with the highest expression levels in the brain, suggesting a role in the local brain metabolism of psychotropic drugs and the existence of endogenous substrates. The genetic polymorphism of CYP2D6, which causes individual...

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PMID: 27918912
DOI: 10.1016/j.pscychresns.2016.11.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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