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Article

Umbilical Cord-derived Mesenchymal Stem Cells Instruct Monocytes Towards an IL10-producing Phenotype by Secreting IL6 and HGF.

Scientific reports - 5 Dec 2016

Deng Yinan, Zhang Yingcai, Ye Linsen, Zhang Tong, Cheng Jintao, Chen Guihua, Zhang Qi, Yang Yang

Abstract excerpt

Human UC-MSCs are regarded as an attractive alternative to BM-MSCs for clinical applications due to their easy preparation, higher proliferation and lower immunogenicity. However, the mechanisms underlying immune suppression by UC-MSCs are still unclear. We studied the mechanism of inhibition by UC-MSCs during the differentiation of monocytes into DCs and focused on the specific source and the role of the...

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Source

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Identifiers

PMID: 27917866
DOI: 10.1038/srep37566
PMCID: PMC5137158

Genes

HGF
MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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