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The brown adipocyte differentiation pathway in birds: An evolutionary road not taken

21 Apr 2008

Abstract excerpt

BACKGROUND: Thermogenic brown adipose tissue has never been described in birds or other non-mammalian vertebrates. Brown adipocytes in mammals are distinguished from the more common white fat adipocytes by having numerous small lipid droplets rather than a single large one, elevated numbers of mitochondria, and mitochondrial expression of the nuclear gene UCP1, the uncoupler of oxidative phosphorylation...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 18426587
DOI: 10.1186/1741-7007-6-17

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