Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Finding sRNA-associated phenotypes by competition assays: An example with Staphylococcus aureus.

Methods (San Diego, Calif.) - 15 Mar 2017

Le Lam Thao Nguyen, Morvan Claire, Liu Wenfeng, Bohn Chantal, Jaszczyszyn Yan, Bouloc Philippe

Abstract excerpt

Bacteria optimize their fitness in response to a changing environment by tight regulation of gene expression. Regulation can be controlled at both transcriptional and post-transcriptional levels via key players such as sigma factors, regulatory proteins and regulatory RNAs. The identification of phenotypes associated with gene deletions is the established method for finding gene functions but may require testing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Assay
Share to DNA Barcoding, Taxonomic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Fitness

Share to Microbial Interactions

Share to RNA, Bacterial

Share to RNA, Small Untranslated

Share to Sigma Factor

Share to Transformation, Bacterial

Source

Identifiers

PMID: 27916561
DOI: 10.1016/j.ymeth.2016.11.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Finding sRNA-associated phenotypes by competition assays: An example with Staphylococcus aureus.PMID 27916561Read ↗

Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking ConditionsSemantic proximity Read ↗

Thirty Years of sRNA-Mediated Regulation in Staphylococcus aureus: From Initial Discoveries to In Vivo Biological ImplicationsSemantic proximity Read ↗

Assembling the Current Pieces: The Puzzle of RNA-Mediated Regulation in Staphylococcus aureusSemantic proximity Read ↗

Emerging Functions for the Staphylococcus aureus RNomeSemantic proximity Read ↗

The Staphylococcus aureus RNome and its commitment to virulence.Semantic proximity Read ↗

Whole-genome sequencing of Staphylococcus aureus strain RN4220, a key laboratory strain used in virulence research, identifies mutations that affect not only virulence factors but also the fitness of the strain.Semantic proximity Read ↗

Dual transposon sequencing (Dual Tn-seq) to probe genome-wide genetic interactionsSemantic proximity Read ↗

The δ Subunit of RNA Polymerase Guides Promoter Selectivity and Virulence in Staphylococcus aureusSemantic proximity Read ↗

sRNA and cis-antisense sRNA identification in Staphylococcus aureus highlights an unusual sRNA gene cluster with one encoding a secreted peptideSemantic proximity Read ↗

The two-component system WalKR provides an essential link between cell wall homeostasis and DNA replication in Staphylococcus aureusSemantic proximity Read ↗

The two-component regulator WalKR provides an essential link between cell wall homeostasis with DNA replication in <i>Staphylococcus aureus</i>Semantic proximity Read ↗

sRNA-controlled iron sparing response in StaphylococciSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.