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Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions

1 Apr 2016

Abstract excerpt

Staphylococcus aureus is a major pathogen that colonizes about 20% of the human population. Intriguingly, this Gram-positive bacterium can survive and thrive under a wide range of different conditions, both inside and outside the human body. Here, we investigated the transcriptional adaptation of S. aureus HG001, a derivative of strain NCTC 8325, across experimental conditions ranging from optimal growth in vitro...

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PMID: 27035918
DOI: 10.1371/journal.pgen.1005962

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