Article
DAPK Promoter Methylation and Bladder Cancer Risk: A Systematic Review and Meta-Analysis.
PloS one - 1 Jan 2016
Dai Lihe, Ma Chong, Zhang Zhensheng, Zeng Shuxiong, Liu Anwei, Tang Shijie, Ren Qian, Sun Yinghao, Xu Chuanliang
Abstract excerpt
BACKGROUND: Methylation of tumor suppressor gene promoter leads to transcription inactivation and is involved in tumorigenesis. Several studies demonstrate a potential association between the Death-Associated Protein Kinase (DAPK) gene promoter methylation and bladder cancer risk, tumor stage and histological grade. Due to inconsistent results of these studies, we performed this meta-analysis to ascertain the...
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