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Article

Suppression of AIMP1 protects cognition in Alzheimer's disease model mice 3xTg-AD.

Neuroreport - 18 Jan 2017

Jang Sooah, Lee Jung Ho, Sohn Bo Kyung, Kim Eosu, Park Sang Gyu, Yoon Kang Jun, Park Minsun, Kim Eun Woo, Jeong Jihyeon, Lee Jun-Young, Kim Chul Hoon, Namkoong Kee

Abstract excerpt

Neuroinflammation has been raised as a candidate of unifying pathogenesis and a target of a disease-modifying strategy for Alzheimer's disease (AD). Aminoacyl-tRNA synthetase complex (ARS)-interacting multifunctional protein 1 (AIMP1) is a cytokine that is known to amplify the actions of tumor necrosis factor-α and to be involved in microglial activation and neuronal death. In this respect, AIMP1 could be a...

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Source

Identifiers

PMID: 27906773
DOI: 10.1097/WNR.0000000000000710

Genes

AIMP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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