Article
Candida guilliermondii as a potential biocatalyst for the production of long-chain α,ω-dicarboxylic acids.
Biotechnology letters - 1 Mar 2017
Werner Nicole, Dreyer Miriam, Wagner Wenke, Papon Nicolas, Rupp Steffen, Zibek Susanne
Abstract excerpt
OBJECTIVES: To explore Candida guilliermondii for the production of long-chain dicarboxylic acids (DCA), we performed metabolic pathway engineering aiming to prevent DCA consumption during β-oxidation, but also to increase its production via the ω-oxidation pathway. RESULTS: We identified the major β- and ω-oxidation pathway genes in C. guilliermondii and performed first steps in the strain improvement. A double...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.