Article
Saliva exosomes from pancreatic tumor-bearing mice modulate NK cell phenotype and antitumor cytotoxicity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Mar 2017
Katsiougiannis Stergios, Chia David, Kim Yong, Singh Ram P, Wong David T W
Abstract excerpt
Tumor exosomes are emerging as antitumor immunity regulators; however, their effects on secondary exosome secretion by distal organs have not been explored. We have previously demonstrated that suppression of exosomes at the distal tumor site of pancreatic ductal adenocarcinoma (PDAC) ablated the development of salivary biomarker profile. Here, we explore the function of salivary exosomes from tumor-bearing mice...
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